There are many services that allow you to tweet without having to log into twitter.com.  If you are thinking about using a third-party service, then the best one to use is the one that suites your work style the best.  Here is a rundown of a few of the services out there:
1) Tweetdeck allows for multiple accounts to be run in a multi-column format.  It is easy to navigate the system and set up searches through global tweets. URLs can be shortened from the interface and can also link to your Facebook account.
2) If you want the option to start with a free version and possibly upgrade to more features for a price, Hootsuite may be for you!  This program allows you to add multiple social networking sites to one location and set up a schedule of posts to each.  Images can be attached to your postings and you can easily shorten links through the easy-to-navigate interface.
3) Seesmic is customizable, but lacks the ability to schedule updates.  If you are new to using a third-party service for tweeting and don’t need the bells and whistles, then this may be the program for you.
4) CoTweet is great if you have multiple people participating in the creation and execution of Twitter messages.  Just as its’ name implies, many people can log in and use this service and users can assign tasks to each other to help ensure a clean transition between users.
5)  BirdHerd is good for people who must manage multiple accounts.  It is not as user-friendly, but allows the use of direct messages from one account to control multiple accounts.
6) Brizzly integrates multimedia like Google Wave.  It allows private conversations between multiple users.  If you were a fan of Google Wave, this might be what you crave!
With all the options out there for tweeting, the best option is what works for you.  And it’s ok to try and several.  I know I sure did until I found one that works best for me and my work style.  And as my workload increases, I try something new!  Have fun with it, because it’s all about being social.
-Jennifer DeMarco, Marketing Manager